Services
The Infectious Disease Assay Development Core provides the following services to projects from external/internal academia as well as for-profit clients:
List of Services
- Discussion on screening goals, assays and instrument compatibility.
- Primary assay development and optimization. Selection of protocols and controls.
- Validation screening of a small library with a robust optimized assay.
- Screening the complete library of compounds (single or multiple compound concentrations, drug combinations).
- Data analysis and storage.
- Secondary screen development and/or screening of primary hits.
- Plating various dilutions of compounds and siRNA libraries.
- Hit to Lead optimization screens.
- Exploring bioactivity of novel compounds, peptides or purifed natural products for activity in antibacterial (e.g ESKAPE organisms, mycobacterium) panels, anti-viral (e.g Infectious HIV) assays and other mechanism of action assays.
- Provide grant support : letters of recommendation, facilty resources, preliminary pilot screening data.